About this Research Topic
Numerous microorganisms colonize the gastrointestinal tract playing critical roles concerning digestion and absorption of dietary nutrients and the regulation of important functions, including host metabolism, immunity, and intestinal barrier function. Increasing evidence suggests that food encompassing nutrients and polyphenols are strong drivers shaping the composition and function of the gut microbiota and mediate the host's physiological activities directly or indirectly. However, the mechanisms involved in the interactions between food nutrients/prebiotics, gut microbiota and host health have not been enlightened to a wide extent.
In this Research Topic, manuscripts focusing on the nutrient-gut microbiota interaction, its role in the development of dysbiosis (imbalance) and low-grade inflammation during the intestinal barrier dysfunction and metabolic disorders are especially welcome. Understanding the molecular mechanisms that regulate gut microbiota and its metabolic activity by dietary nutrients may be useful in developing dietary approaches to improve human health via a precision microbiome modulation. We hope to attract both research and review articles that contribute to and describe the field's current status, respectively.
Potential topics include but not limited to the following:
• Modulation of gut microbiome composition and function by food nutrients in metabolic disorders or inflammation-related intestinal diseases
• The possible mechanisms for the microbial metabolites derived from dietary in mediating host physiological activities
• The microbe-microbe interactions in the face of nutritional intervention, including microbial communication and signalling
• Crosstalk among diet, gut microbiota and gut health/host metabolism
• Development of nutritional strategies to precisely modulate gut microbiome and gut health
In this Research Topic, manuscripts focusing on the nutrient-gut microbiota interaction, its role in the development of dysbiosis (imbalance) and low-grade inflammation during the intestinal barrier dysfunction and metabolic disorders are especially welcome. Understanding the molecular mechanisms that regulate gut microbiota and its metabolic activity by dietary nutrients may be useful in developing dietary approaches to improve human health via a precision microbiome modulation. We hope to attract both research and review articles that contribute to and describe the field's current status, respectively.
Potential topics include but not limited to the following:
• Modulation of gut microbiome composition and function by food nutrients in metabolic disorders or inflammation-related intestinal diseases
• The possible mechanisms for the microbial metabolites derived from dietary in mediating host physiological activities
• The microbe-microbe interactions in the face of nutritional intervention, including microbial communication and signalling
• Crosstalk among diet, gut microbiota and gut health/host metabolism
• Development of nutritional strategies to precisely modulate gut microbiome and gut health
Keywords: food nutrients, bioactive food ingredients, polyphenol, gut microbiota, commensal microbial ecology, microbe-microbe interactions, precise microbiome, gut health, gut leaks
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
